Are High Histamine Levels making you Stressed and Anxious?

by | Apr 7, 2022 | Mental Health, Stress & Fatigue

Do you struggle with poor stress tolerance, anxiety and episodes of low mood, depression even? Do you have perfectionistic tendencies and maintain high standards and expect a lot from life and yourself? Do you find that your very own high expectations leave you feeling overwhelmed and stressed? Did you know that all of these traits and mood problems can be due to an imbalance in a neurotransmitter in your brain called histamine?

We frequently see people in our practice that have high neurological histamine issues. They possess what we term a “high histamine type personality.” It’s not that their body is making too much histamine, whats happening is that they are not clearing that histamine out of their brain quickly enough and the build up of this excitatory neurotransmitter is negatively impacting how they feel and behave.

Histamine is a neurotransmitter that, like glutamate has an excitatory impact on the brain. Most will point to external factors, such as work or home stress, as the smoking gun in this case, but when we look more closely, we frequently discover that histamine is primarily to blame. Managing the neurological levels of histamine in the brain is beneficial for performance at work, happiness at home, and general well-being since it plays a role in the management of stress and anxiety.


 The Clues

High histamine types tend to display a combination of the following character traits:

  • High academic achievers
  • Highly motivated individuals
  • Carrying inner anxiety with a calm exterior
  • Being competitive with themselves and/or others
  • Having obsessive compulsive or ritualistic behaviours
  • Having the need for a strong sense of routine, order or control over things

High-histamine types are intelligent, productive, and successful in both their careers and personal lives when they are in balance. It’s when the histamine levels become excessive, problems begin to arise. It frequently takes the form of stress and worry, sadness, and a decreased threshold for stress.



One way to combat this issue is by reducing your exposure to foods high in histamine. People have found that eliminating foods high in histamine can dramatically help, some of these foods includes:

  • Alcohol
  • Pickled foods
  • Chocolate
  • Nuts, beans and pulses
  • Cured meats and aged cheeses

ment for assisting with histamine clearance is to use the nutritional cofactor for the enzyme that degrades histamine in the brain. It’s called histamine-n-methyl transferase. That cofactor is s-adenosyl-methionine (SAMe).

However, there is a potential danger here in self prescribing SAMe. While SAMe does help to eliminate extra histamine from the circulation, We strongly urge you to work with a qualified and experienced naturopath or integrative doctor to administer this nutrient. If you self-prescribe, things could go horribly wrong.


Behavioural Change

Those caught in the high achieving, perfectionist cycle should also reach out for help with a psychologist or psychotherapist to examine the underlying causes of their patterns of behaviour, and address them.

If you know or suspect you have neurological high histamine issues and would like to work on addressing that, book an initial appointment with one of our highly experienced nutritionists or naturopaths at Radius Health.

Book your in person or telehealth appointment with us today!

Meet Our Practitioners

Bec Stone

Susan Hunter

Bec Stone

Bec Stone

Georgie Stephen

Georgie Stephen

Sharda Shrivastava

Sophie Kane

Sharda Shrivastava

Carolyn Howard

Better Health Care is Our Mission

Same Day Appointments are Available.


(03) 7064 5222